Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons
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چکیده
منابع مشابه
Interferons direct an effective innate response to Legionella pneumophila infection.
Legionella pneumophila remains an important opportunistic pathogen of human macrophages. Its more limited ability to replicate in murine macrophages has been attributed to redundant innate sensor systems that detect and effectively respond to this infection. The current studies evaluate the role of one of these innate response systems, the type I interferon (IFN-I) autocrine loop. The ability o...
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PURPOSE OF REVIEW Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen is considered a potential biological threat agent. This review focuses on the most recent literature highlighting host innate immune response to B. ...
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ژورنال
عنوان ژورنال: Cell Reports Medicine
سال: 2020
ISSN: 2666-3791
DOI: 10.1016/j.xcrm.2020.100146